CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9126
Family Name Histamine H4 receptor ligand 8-chloro-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrido[2,3]furo[2,4-b]pyrimidin-2-amine family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00393180 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Mast/stem cell growth factor receptor Kit Ligand MP470 Superfamily
Class Class 899

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
MK-3328 family 2 32
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Histamine H4 receptor and Histamine H3 receptor ligand SureCN6... 17 51
Adenosine kinase inhibitor 7-[(4aS,7aS)-6-benzyl-3,4,4a,5,7,7a... 2 1
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor CHEM... 1 0
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Prothrombin inhibitor SureCN6925359 family 6 18
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393180 CHEMBL1915048 Bioactive 8-chloro-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrido[2,3]furo[2,4-b]pyrimidin-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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