CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9129
Family Name Serine/threonine-protein kinase pim-2 and Serine/threonine-protein kinase pim-1 inhibitor (4E)-3-chloro-4-[[(7Z)-7-(1,2-dihydro-1,2,4-triazol-3-ylidene)-2H-benzo[c][2,6]naphthyridin-5-yl]imino]cyclohexa-2,5-dien-1-one family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00393192 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-2 Binder Superfamily 3
Class Class 795

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Tyrosine kinase Inhibitor PKI166 Family 17 198
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Aurora kinase B inhibitor AGN-PC-07ZZ0Y family 2 12
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
TGF-beta receptor type-1 ligand 3-(6-methylpyridin-2-yl)-N-phe... 21 0
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 0
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-[4-... 1 0
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-07CQG5 ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393195 CHEMBL2017341 Bioactive 3-chloro-4-[[6-(1H-1,2,4-triazol-5-yl)thieno[3,2-c]quinolin-4-yl]amino]phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

39005 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543