CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9134
Family Name Serine/threonine-protein kinase pim-2 and Serine/threonine-protein kinase pim-1 inhibitor 5-(2-chloro-3-methoxyanilino)-N-methylbenzo[c][2,6]naphthyridine-7-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00393213 Functional Category Bioactive
Superfamily Macrophage colony-stimulating factor 1 receptor and Alpha-1D adrenergic receptor Binder Superfamily
Class Class 4398

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
MK-6096 family 3 69
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Metabotropic glutamate receptor 5 ligand AGN-PC-09QLD2 family 1 2
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 0
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 3 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Motilin receptor ligand SureCN2765637 family 1 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0Z0U... 2 0
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393213 CHEMBL1915645 Bioactive 5-(2-chloro-3-methoxyanilino)-N-methylbenzo[c][2,6]naphthyridine-7-carboxamide
CFAMM00393214 CHEMBL246151 Bioactive SureCN1266194

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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