CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9144
Family Name Collagenase 3 and 72 kDa type IV collagenase inhibitor 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-7-oxo-5,6-dihydro-2H-azepin-6-yl]benzenesulfonamide family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00393261 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 and Matrix metalloproteinase-14 Inhibitor N-hydroxy-2-(4-methoxyphenylsulfonamido)acetamide Superfamily
Class Class 2682

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 15 129
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor (3S)-3-[[... 5 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Disintegrin and metalloproteinase domain-containing protein 17... 6 12
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 4
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393265 CHEMBL1916054 Bioactive 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-3-(morpholin-4-ylmethyl)-7-oxo-5,6-dihydro-2H-azepin-6-yl]benzenesulfonamide
CFAMM00393258 CHEMBL1916211 Bioactive 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-7-oxo-5,6-dihydro-2H-azepin-6-yl]-N-(2-piperidin-1-ylethyl)benzenesulfonamide
CFAMM00393264 CHEMBL1916053 Bioactive 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-3-methyl-7-oxo-5,6-dihydro-2H-azepin-6-yl]benzenesulfonamide
CFAMM00393263 CHEMBL1916210 Bioactive 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-7-oxo-5,6-dihydro-2H-azepin-6-yl]-N-(2-morpholin-4-ylethyl)benzenesulfonamide
CFAMM00393262 CHEMBL1916051 Bioactive 4-(4-chlorophenoxy)-N-[(3R)-1-hydroxy-2-oxoazepan-3-yl]benzenesulfonamide
CFAMM00393261 CHEMBL1916050 Bioactive 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-7-oxo-5,6-dihydro-2H-azepin-6-yl]benzenesulfonamide
CFAMM00393266 CHEMBL1916212 Bioactive 4-(4-chlorophenoxy)-N-[(6R)-1-hydroxy-7-oxo-5,6-dihydro-2H-azepin-6-yl]-N-[2-(4-methylpiperazin-1-yl)ethyl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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