CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9179
Family Name Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-[(6-ethoxynaphthalen-2-yl)sulfonyl-(3-methylbutyl)amino]-N-hydroxy-3-methylbutanamide family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00255239 Functional Category Bioactive
Superfamily Collagenase 3 and 72 kDa type IV collagenase Binder Superfamily 5
Class Class 3248

Cousin Family NamesSeedsMembers
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Trypsin Inhibitor Benzamidrazone Analogue Family 2 6 38
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Cathepsin K inhibitor SureCN6578603 family 1 3
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor AC1L4BQ... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Interstitial collagenase and 72 kDa type IV collagenase inhibi... 1 1
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Growth hormone secretagogue receptor type 1 ligand 2-benzylsul... 2 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 1
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 6-hydr... 1 5
Macrophage metalloelastase inhibitor 2-(2,5-dichlorophenyl)sul... 1 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Macrophage metalloelastase and Collagenase 3 inhibitor N-hydro... 2 3
72 kDa type IV collagenase and Disintegrin and metalloproteina... 5 1
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 12 20
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
Neutrophil elastase inhibitor 2-[3-[(4-methoxyphenyl)sulfonyla... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
Cathepsin L1 and Cathepsin B inhibitor (2S)-N-[(2S)-1-(4-hydro... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 4 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Prothrombin inhibitor 2-[4-[(4,6-dimethoxynaphthalen-2-yl)sulf... 3 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393487 CHEMBL1916661 Bioactive (2R)-N-hydroxy-2-[(6-hydroxynaphthalen-2-yl)sulfonyl-(3-methylbutyl)amino]-3-methylbutanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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