CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9182
Family Name Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-[2,3-dihydro-1-benzofuran-5-ylsulfonyl(3-methylbutyl)amino]-N-hydroxy-3-methylbutanamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00393501 Functional Category Bioactive
Superfamily Collagenase 3 and 72 kDa type IV collagenase Binder Superfamily 5
Class Class 3248

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Collagenase 3 and Interstitial collagenase inhibitor AGN-PC-01... 10 1
Cathepsin K inhibitor SureCN6578603 family 1 3
Collagenase 3 and Interstitial collagenase inhibitor (1R,5S)-3... 2 1
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor AC1L4BQ... 3 0
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Leukotriene A-4 hydrolase inhibitor 3-[3-(4-benzylphenoxy)prop... 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 5
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Trypsin-1 and Trypsin-2 inhibitor 4-[3-[(3S)-3-(2,3-dihydro-1-... 3 7
Disintegrin and metalloproteinase domain-containing protein 17... 4 2
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
Disintegrin and metalloproteinase domain-containing protein 17... 6 12
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor 4-(4-ch... 7 6
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Macrophage metalloelastase and Collagenase 3 inhibitor N-hydro... 2 3
Macrophage metalloelastase and Collagenase 3 inhibitor (2S)-N-... 2 2
72 kDa type IV collagenase and Disintegrin and metalloproteina... 5 1
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Disintegrin and metalloproteinase domain-containing protein 17... 13 1
Neutrophil elastase inhibitor 1-[(2S)-2-[(4-methoxyphenyl)sulf... 2 11
Neutrophil elastase inhibitor 2-[3-[(4-methoxyphenyl)sulfonyla... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 4 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[2-(3-methoxyp... 1 0
Bone morphogenetic protein 1 inhibitor N-hydroxy-3-[[4-[(Z)-N'... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393501 CHEMBL1916839 Bioactive (2R)-2-[2,3-dihydro-1-benzofuran-5-ylsulfonyl(3-methylbutyl)amino]-N-hydroxy-3-methylbutanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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