CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9196
Family Name Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methyl]indol-1-yl]acetic acid family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00393608 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 and Prostaglandin D2 receptor 2 Binder Superfamily
Class Class 3264

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Prostaglandin D2 receptor 2 Ligand AZD1981 Family 11 28
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03VWKZ family 2 34
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Prostaglandin D2 receptor 2 and Aldose reductase ligand 2-[5-c... 1 0
Prostaglandin D2 receptor 2 ligand 2-[3-(4-chlorophenyl)sulfan... 2 1
Prostaglandin D2 receptor 2 ligand SureCN317401 family 3 8
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 2 0
Prostaglandin D2 receptor 2 and Cytochrome P450 2C19 ligand 2-... 6 13
Prostaglandin D2 receptor 2 ligand 2-[3-[(E)-2-cyano-3-(N-meth... 9 9
Prostaglandin G/H synthase 2 inhibitor 1-(3-fluorophenyl)-2-me... 1 5
Prostaglandin G/H synthase 2 inhibitor 1-(3,4-difluorophenyl)-... 1 3
Prostaglandin D2 receptor 2 ligand SureCN2516080 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393609 CHEMBL2385124 Bioactive 2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00393608 CHEMBL2181804 Bioactive 2-[5-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methyl]indol-1-yl]acetic acid
CFAMM00393606 CHEMBL1917443 Bioactive 2-[2,5-dimethyl-3-(4-methylsulfonylphenyl)sulfanylindol-1-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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