CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9198
Family Name Prostaglandin D2 receptor 2 ligand 2-[3-(4-chlorophenoxy)-5-fluoro-2-methylindol-1-yl]acetic acid family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00393618 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor 2 and Thromboxane A2 receptor Binder Superfamily
Class Class 409

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Dihydroorotate dehydrogenase Inhibitor LY214352 Family 2 17
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Neuropeptide Y receptor type 1 ligand SureCN7959923 family 1 6
5-hydroxytryptamine receptor 2A and Alpha-1A adrenergic recept... 4 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Prostaglandin E synthase 2 inhibitor AGN-PC-075D2E family 1 0
D(4) dopamine receptor ligand AGN-PC-00FE9S family 1 6


External ID

Functional Category

Molecule Name

CFAMM00393618 CHEMBL1917454 Bioactive 2-[3-(4-chlorophenoxy)-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00393616 CHEMBL1917456 Bioactive 2-[3-(4-chlorophenoxy)-4-(methanesulfonamido)-2-methylindol-1-yl]acetic acid
CFAMM00393619 CHEMBL1917460 Bioactive 2-[3-(4-chlorophenoxy)-2-methyl-4-phenylindol-1-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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