CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM920
Family Name Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 ligand CHEMBL2205921 family
No. of Seeds 12 No. of Other Members 85
Family Centroid CFAMM00317276 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 and Binder Superfamily
Class Class 427

Cousin Family NamesSeedsMembers
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Epidermal growth factor receptor ligand 1-[4-[[(1S)-2-hydroxy-... 2 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 12
Lutropin-choriogonadotropic hormone receptor and Follicle-stim... 1 3
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family 11 10
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9S6C family 10 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9PTC family 4 1
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 11 7
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4A family 3 0
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4C family 1 0
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 0
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 7 1
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Vascular endothelial growth factor receptor 2 and Vascular end... 4 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 1 0
3-phosphoinositide-dependent protein kinase 1 and Serine/threo... 2 2
Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-... 5 2
Metabotropic glutamate receptor 1 ligand SureCN8238697 family 2 0
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
P2Y purinoceptor 12 inhibitor AGN-PC-00ILFN family 4 11
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 1
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 3 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317280 CHEMBL2205928 Bioactive CHEMBL2205928
CFAMM00317279 CHEMBL2205924 Bioactive CHEMBL2205924
CFAMM00317285 CHEMBL1784055 Bioactive AGN-PC-0A9R6Y
CFAMM00317278 CHEMBL2205927 Bioactive CHEMBL2205927
CFAMM00317300 CHEMBL1093560 Bioactive AGN-PC-07ZYT9
CFAMM00317314 CHEMBL1784072 Bioactive AGN-PC-0A9RU2
CFAMM00317276 CHEMBL2205921 Bioactive CHEMBL2205921
CFAMM00317258 CHEMBL2205370 Bioactive CHEMBL2205370
CFAMM00317351 CHEMBL1093869 Bioactive SureCN8247241
CFAMM00317327 CHEMBL1784068 Bioactive AGN-PC-0A9R70
CFAMM00317287 CHEMBL1784059 Bioactive AGN-PC-0A9R6Z
CFAMM00317304 CHEMBL1951887 Bioactive 4-(dimethylamino)-7-(4-methylphenyl)pyrido[4,5]thieno[1,2-c]pyrimidin-8-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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