CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9205
Family Name Substance-P receptor ligand (3R,4S)-N-ethyl-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidine-1-carboxamide;hydrochloride family
No. of Seeds 22 No. of Other Members 3
Family Centroid CFAMM00393690 Functional Category Bioactive
Superfamily Substance-P receptor and Prelamin-A/C Binder Superfamily
Class Class 4700

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Substance-P receptor ligand (2S,3S)-N-[[2-methoxy-5-(tetrazol-... 2 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393684 CHEMBL1917859 Bioactive (3R,4S)-N-cyclopropyl-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidine-1-carboxamide;hydrochloride
CFAMM00393699 CHEMBL1917862 Bioactive 1-[3-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidine-1-carbonyl]azetidin-1-yl]ethanone;hydrochloride
CFAMM00393690 CHEMBL1917853 Bioactive (3R,4S)-N-ethyl-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidine-1-carboxamide;hydrochloride
CFAMM00393705 CHEMBL1917864 Bioactive N-[2-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidin-1-yl]-2-oxoethyl]acetamide
CFAMM00393682 CHEMBL522302 Bioactive Vofopitant
CFAMM00393697 CHEMBL1917849 Bioactive (3R,4S)-1-ethyl-N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-3-phenylpiperidin-4-amine;hydrochloride
CFAMM00393689 CHEMBL1917854 Bioactive Vofopitant dihydrochloride
CFAMM00393704 CHEMBL1917867 Bioactive N-[2-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidin-1-yl]-2-oxoethyl]-N-methylacetamide;hydrochloride
CFAMM00393696 CHEMBL1917848 Bioactive (3R,4S)-N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-3-phenylpiperidin-4-amine;hydrochloride
CFAMM00393688 CHEMBL1917855 Bioactive (3R,4S)-4-[[2-ethoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-N-ethyl-3-phenylpiperidine-1-carboxamide;hydrochloride
CFAMM00393703 CHEMBL1917866 Bioactive N-[4-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidin-1-yl]-4-oxobutyl]acetamide;hydrochloride
CFAMM00393687 CHEMBL1917856 Bioactive (3R,4S)-4-[[2-cyclopropyloxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-N-ethyl-3-phenylpiperidine-1-carboxamide;hydrochloride
CFAMM00393702 CHEMBL1917861 Bioactive (3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-N,N-dimethyl-3-phenylpiperidine-1-carboxamide;hydrochloride
CFAMM00393693 CHEMBL1917850 Bioactive (3R,4S)-N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-1-methylsulfonyl-3-phenylpiperidin-4-amine
CFAMM00393686 CHEMBL1917857 Bioactive (3R,4S)-N-ethyl-3-phenyl-4-[[5-[5-(trifluoromethyl)tetrazol-1-yl]-2,3-dihydro-1-benzofuran-7-yl]methylamino]piperidine-1-carboxamide
CFAMM00393701 CHEMBL1917860 Bioactive (3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenyl-N-(2,2,2-trifluoroethyl)piperidine-1-carboxamide;hydrochloride
CFAMM00393692 CHEMBL1917851 Bioactive methyl (3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidine-1-carboxylate
CFAMM00393707 CHEMBL1917869 Bioactive N-[2-[(3R,4R)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidin-1-yl]-2-oxoethyl]acetamide;hydrochloride
CFAMM00393685 CHEMBL1917858 Bioactive (3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenyl-N-propan-2-ylpiperidine-1-carboxamide;hydrochloride
CFAMM00393700 CHEMBL1917863 Bioactive 1-[4-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidine-1-carbonyl]piperidin-1-yl]ethanone;hydrochloride
CFAMM00393691 CHEMBL1917852 Bioactive 1-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidin-1-yl]ethanone;hydrochloride
CFAMM00393706 CHEMBL1917865 Bioactive N-[3-[(3R,4S)-4-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methylamino]-3-phenylpiperidin-1-yl]-3-oxopropyl]acetamide;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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