CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9211
Family Name Serine/threonine-protein kinase Chk2 inhibitor SureCN3922132 family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00393734 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 and Serine/threonine-protein kinase Chk2 Binder Superfamily
Class Class 2756

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Tubulin beta chain Inhibitor Mebendazole Family 12 84
BIBT986 family 7 96
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Coagulation factor X inhibitor 3-[2-(5-chlorothiophen-2-yl)-3H... 1 10
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Coagulation factor X and Trypsin-1 inhibitor 5-(3-carbamimidoy... 2 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 2
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Prostaglandin E synthase inhibitor 2-(2-chloro-6-fluorophenyl)... 9 1
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene... 1 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0
Acyl-CoA desaturase 1 inhibitor N-(thiophen-2-ylmethyl)-2-[4-[... 2 0


External ID

Functional Category

Molecule Name

CFAMM00393735 CHEMBL195177 Bioactive SureCN3926044
CFAMM00393734 CHEMBL193990 Bioactive SureCN3922132
CFAMM00393733 CHEMBL191969 Bioactive SureCN3921862

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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