CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9212
Family Name 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 1B ligand 5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00393739 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and 5-hydroxytryptamine receptor 1B Binder Superfamily
Class Class 471

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Transient receptor potential cation channel subfamily V member... 15 158
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
Transient receptor potential cation channel subfamily V member... 3 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE ... 4 4
Prostaglandin E synthase and Aldo-keto reductase family 1 memb... 3 12
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Sterol O-acyltransferase 1 inhibitor SureCN7073167 family 4 2


External ID

Functional Category

Molecule Name

CFAMM00393739 CHEMBL191971 Bioactive 5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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