CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM922
Family Name Orexin receptor type 1 and Orexin receptor type 2 ligand AGN-PC-07ZC2O family
No. of Seeds 2 No. of Other Members 24
Family Centroid CFAMM00317370 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Orexin receptor type 2 Binder Superfamily
Class Class 96

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 4
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 3
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Smoothened homolog inhibitor SureCN1091571 family 2 2
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 10 0
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
P2X purinoceptor 7 inhibitor SureCN109074 family 3 8
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Alpha-1B adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
Glutamate racemase inhibitor 5-[5-but-2-ynyl-2-[(6-chloroquino... 9 8
Glutamate racemase inhibitor AGN-PC-077KKZ family 6 0
Glutamate racemase inhibitor AGN-PC-077KMZ family 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317370 CHEMBL1093725 Bioactive AGN-PC-07ZC2O
CFAMM00317383 CHEMBL1172520 Bioactive [5-chloro-2-(triazol-2-yl)phenyl]-[(1R,5R)-6-(6-fluoroquinazolin-2-yl)-3,6-diazabicyclo[3.2.1]octan-3-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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