CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9227
Family Name C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S)-3-ethyl-4-[1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]piperazin-1-yl]pyrazine-2-carboxamide family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00393819 Functional Category Bioactive
Superfamily Sodium/hydrogen exchanger 1 Inhibitor 5'-(n-ethyl-n-isopropyl)amiloride Superfamily
Class Class 2496

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Survival motor neuron protein and Microtubule-associated prote... 2 14
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 13 2
Amiloride-sensitive sodium channel subunit alpha ligand 3,5-di... 5 19
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 10 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393819 CHEMBL1921859 Bioactive 3-amino-6-chloro-5-[(3S)-3-ethyl-4-[1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]piperazin-1-yl]pyrazine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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