CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9260
Family Name Hepatocyte growth factor receptor ligand 5-[[6-(3-hydroxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]-2H-isoquinolin-1-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00393992 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Niemann-Pick C1 protein Binder Superfamily
Class Class 4316

Cousin Family NamesSeedsMembers
Ibrutinib family 2 27
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 4 32
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Smoothened homolog inhibitor SureCN1091571 family 2 2
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 4
Adenosine receptor A3 ligand CHEMBL1834703 family 2 1
Hepatocyte growth factor receptor ligand 5-[[6-(1-methylpyrazo... 4 0
Hepatocyte growth factor receptor ligand 5-[(6-phenyl-[1,2,4]t... 6 2
Hepatocyte growth factor receptor ligand 5-[(6-thiophen-3-yl-[... 1 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-3-... 13 1
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00393990 CHEMBL1922420 Bioactive 5-[[6-(3-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]-2H-isoquinolin-1-one
CFAMM00393992 CHEMBL1922419 Bioactive 5-[[6-(3-hydroxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]-2H-isoquinolin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38798 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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