CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9262
Family Name Arachidonate 5-lipoxygenase-activating protein inhibitor SureCN3469369 family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00394004 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase Inhibitor MK-591 Superfamily
Class Class 958

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Arachidonate 5-lipoxygenase-activating protein Inhibitor AM103... 14 12
Peroxisome proliferator-activated receptor delta ligand SureCN... 3 4
Arachidonate 5-lipoxygenase-activating protein inhibitor SureC... 5 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Cysteinyl leukotriene receptor 1 ligand 3-[1-[3-[(7-chloroquin... 5 6
Aldose reductase and Alcohol dehydrogenase [NADP(+)] inhibitor... 3 2
Cytochrome P450 3A4 and Cytochrome P450 2D6 inhibitor SureCN16... 8 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 17
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Arachidonate 5-lipoxygenase inhibitor SureCN6008522 family 1 6
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
Arachidonate 5-lipoxygenase-activating protein inhibitor 3-[5-... 1 0
Arachidonate 5-lipoxygenase-activating protein inhibitor AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394003 CHEMBL610474 Bioactive SureCN3478523
CFAMM00394009 CHEMBL595872 Bioactive 3-[5-[[(2S)-1-acetyl-2,3-dihydroindol-2-yl]methoxy]-3-tert-butylsulfanyl-1-[[4-(5-fluoropyridin-2-yl)phenyl]methyl]indol-2-yl]-2,2-dimethylpropanoic acid
CFAMM00394002 CHEMBL1922650 Bioactive 3-[3-tert-butylsulfanyl-1-[[4-(6-methoxypyridin-3-yl)phenyl]methyl]-5-[(5-methyl-1,2-oxazol-3-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoic acid
CFAMM00394008 CHEMBL1922649 Bioactive 3-[3-tert-butylsulfanyl-1-[[4-(6-methoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyrazin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoic acid
CFAMM00394007 CHEMBL1922667 Bioactive 3-[3-tert-butylsulfanyl-5-[(5-methylpyridin-2-yl)methoxy]-1-[[4-(6-oxo-1H-pyridin-3-yl)phenyl]methyl]indol-2-yl]-2,2-dimethylpropanoic acid
CFAMM00394005 CHEMBL1922524 Bioactive 3-[3-tert-butylsulfanyl-1-[[4-(6-methoxypyridin-3-yl)phenyl]methyl]-5-(quinoxalin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid
CFAMM00394004 CHEMBL610473 Bioactive SureCN3469369

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543