CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9264
Family Name Cytochrome P450 3A4 and Cytochrome P450 2D6 inhibitor SureCN169607 family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00394015 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase and Cytochrome P450 3A4 Binder Superfamily
Class Class 958

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Arachidonate 5-lipoxygenase-activating protein Inhibitor AM103... 14 12
Peroxisome proliferator-activated receptor delta ligand SureCN... 3 4
Arachidonate 5-lipoxygenase-activating protein inhibitor SureC... 5 0
Cysteinyl leukotriene receptor 1 ligand 3-[1-[3-[(7-chloroquin... 5 6
Aldose reductase and Alcohol dehydrogenase [NADP(+)] inhibitor... 3 2
Arachidonate 5-lipoxygenase-activating protein inhibitor SureC... 8 1
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 6 0
Arachidonate 5-lipoxygenase inhibitor SureCN6008522 family 1 6
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 1
Arachidonate 5-lipoxygenase-activating protein inhibitor 3-[5-... 1 0
Arachidonate 5-lipoxygenase-activating protein inhibitor AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394020 CHEMBL552545 Bioactive SureCN176015
CFAMM00394013 CHEMBL610472 Bioactive SureCN4195152
CFAMM00394012 CHEMBL555209 Bioactive SureCN169920
CFAMM00394017 CHEMBL553403 Bioactive SureCN170221
CFAMM00394023 CHEMBL557548 Bioactive SureCN175792
CFAMM00394015 CHEMBL539650 Bioactive SureCN169607
CFAMM00394021 CHEMBL538955 Bioactive SureCN166785
CFAMM00394014 CHEMBL1922656 Bioactive 3-[3-tert-butylsulfanyl-1-[[4-(2-ethoxy-1,3-thiazol-4-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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