CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9271
Family Name ALK tyrosine kinase receptor and Insulin receptor ligand (4Z,5Z)-4-[[4-[(3-chloro-2,6-difluorophenyl)methoxy]-1-methylindol-3-yl]methylidene]-5-(4-methyl-2H-thiadiazol-5-ylidene)pyrazol-3-one family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00394091 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 and Insulin receptor Binder Superfamily
Class Class 4704

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 2 ligand (4Z,5Z)-4... 1 3
Vascular endothelial growth factor receptor 2 ligand (4Z,5Z)-4... 1 1
Vascular endothelial growth factor receptor 2 ligand (4Z)-4-[(... 3 0


External ID

Functional Category

Molecule Name

CFAMM00394091 CHEMBL1922974 Bioactive (4Z,5Z)-4-[[4-[(3-chloro-2,6-difluorophenyl)methoxy]-1-methylindol-3-yl]methylidene]-5-(4-methyl-2H-thiadiazol-5-ylidene)pyrazol-3-one
CFAMM00394084 CHEMBL1922984 Bioactive (4Z)-4-[[4-[(2,6-difluorophenyl)methoxy]-1-methylindol-3-yl]methylidene]-3-(1,3-thiazol-2-yl)-1H-pyrazol-5-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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