CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM929
Family Name Muscarinic acetylcholine receptor M2 and Muscarinic acetylcholine receptor M4 ligand 3-(5-methyl-3-phenylfuran-2-yl)-1-azabicyclo[2.2.2]oct-2-ene family
No. of Seeds 8 No. of Other Members 36
Family Centroid CFAMM00317459 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand A-80426 Superfamily
Class Class 769

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 2
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Sodium-dependent dopamine transporter and Sigma non-opioid int... 7 5
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 0
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
Histamine H3 receptor ligand SureCN2786002 family 8 3
Histamine H3 receptor ligand SureCN2785131 family 7 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and Sigma no... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 0
5-hydroxytryptamine receptor 1A ligand 8-[4-[[(2R)-5-fluoro-8-... 2 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317442 CHEMBL338801 Bioactive 3-[3-(3-ethylphenyl)furan-2-yl]-1-azabicyclo[2.2.2]oct-2-ene
CFAMM00317468 CHEMBL122160 Bioactive SureCN7401950
CFAMM00317454 CHEMBL324913 Bioactive 3-(5-fluoro-1-benzofuran-2-yl)-1-azabicyclo[2.2.2]oct-2-ene
CFAMM00317453 CHEMBL333937 Bioactive 3-[3-[3-(trifluoromethyl)phenyl]furan-2-yl]-1-azabicyclo[2.2.2]oct-2-ene
CFAMM00317459 CHEMBL128035 Bioactive 3-(5-methyl-3-phenylfuran-2-yl)-1-azabicyclo[2.2.2]oct-2-ene
CFAMM00317465 CHEMBL109405 Bioactive SureCN4688548
CFAMM00317450 CHEMBL333670 Bioactive 3-(5-bromo-3-phenylfuran-2-yl)-1-azabicyclo[2.2.2]oct-2-ene
CFAMM00317456 CHEMBL333540 Bioactive 3-[2-(1-azabicyclo[2.2.2]oct-2-en-3-yl)furan-3-yl]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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