CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9304
Family Name Muscarinic acetylcholine receptor M3 ligand (1,1-dimethylpiperidin-1-ium-4-yl) 2-phenyl-2-piperidin-1-ylpropanoate family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00394348 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M3 Binder Superfamily
Class Class 810

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
Muscarinic acetylcholine receptor M2 ligand Tropane alkaloid S... 7 16
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Muscarinic acetylcholine receptor Ligand Cyclopentolate Family 10 11
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 1
Muscarinic acetylcholine receptor M3 ligand SureCN13330671 family 17 1
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-(3-phenylp... 10 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 0


External ID

Functional Category

Molecule Name

CFAMM00394342 CHEMBL1924039 Bioactive [(3R)-1-azabicyclo[2.2.2]octan-3-yl] 2-phenyl-2-pyrrolidin-1-ylpropanoate
CFAMM00394348 CHEMBL1924029 Bioactive (1,1-dimethylpiperidin-1-ium-4-yl) 2-phenyl-2-piperidin-1-ylpropanoate
CFAMM00394347 CHEMBL1924028 Bioactive (1,1-dimethylpiperidin-1-ium-4-yl) 2-phenyl-2-pyrrolidin-1-ylpropanoate
CFAMM00394346 CHEMBL1924030 Bioactive (1,1-dimethylpiperidin-1-ium-4-yl) 2-(azepin-1-yl)-2-phenylpropanoate
CFAMM00394345 CHEMBL1924031 Bioactive (1,1-dimethylpiperidin-1-ium-4-yl) 2-phenyl-2-thiomorpholin-4-ylpropanoate
CFAMM00394344 CHEMBL1924032 Bioactive (1,1-dimethylpiperidin-1-ium-4-yl) 2-(4,4-difluoropiperidin-1-yl)-2-phenylpropanoate
CFAMM00394343 CHEMBL1924038 Bioactive (1-methylpiperidin-4-yl) 2-phenyl-2-pyrrolidin-1-ylpropanoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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