CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9312
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand AGN-PC-004F2I family
No. of Seeds 9 No. of Other Members 6
Family Centroid CFAMM00394417 Functional Category Bioactive with Natural Product
Superfamily B1 bradykinin receptor and Protease Binder Superfamily
Class Class 1253

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Adenosine receptor A3 and Adenosine receptor A1 ligand propyl ... 6 63
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
NS5B protein inhibitor AC1NQMYG family 6 12
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 19
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 22
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 12
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
5-hydroxytryptamine receptor 3A ligand 3-methyl-N-[7-[[3-methy... 2 0
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 22 11
Substance-P receptor ligand Netupitant family 5 2
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
P2Y purinoceptor 12 inhibitor SureCN3925458 family 1 13
Histone deacetylase 1 inhibitor SureCN4538615 family 2 2
P2Y purinoceptor 12 inhibitor SureCN3928692 family 5 0
P2Y purinoceptor 12 inhibitor SureCN3923520 family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394415 CHEMBL372262 Bioactive AGN-PC-007YWQ
CFAMM00394425 CHEMBL195490 Bioactive AGN-PC-007HT7
CFAMM00394424 CHEMBL195881 Bioactive AGN-PC-007IFO
CFAMM00394413 CHEMBL439857 Bioactive AGN-PC-004O4N
CFAMM00394421 CHEMBL289794 Bioactive AGN-PC-073MMS
CFAMM00394418 CHEMBL192930 Bioactive ethyl 2-(4-methylpiperazin-1-yl)quinoline-4-carboxylate
CFAMM00394417 CHEMBL192675 Bioactive AGN-PC-004F2I
CFAMM00394427 CHEMBL41511 Bioactive AGN-PC-00GB1W

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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