CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9332
Family Name Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase ligand 3,3-dimethyl-1-[3-(4,5,6,7-tetrahydro-1-benzothiophen-4-yl)propyl]piperidine;hydrochloride family
No. of Seeds 4 No. of Other Members 12
Family Centroid CFAMM00394540 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 3657

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M5 Ligand Metixene Family 5 24
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Leukotriene A-4 hydrolase Inhibitor N-methyl-1-(2-thiophen-2-y... 2 28
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 39
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 12 20
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Sodium-dependent dopamine transporter Inhibitor 1-(1-benzo[b]t... 5 5
Potassium voltage-gated channel subfamily H member 2 Ligand 3-... 1 4
5-hydroxytryptamine receptor 1A Ligand 2-(biphenyl-3-ylthio)-n... 1 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
5-hydroxytryptamine receptor 1A ligand (2R)-N,N-dipropyl-8-thi... 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Sigma non-opioid intracellular receptor 1 ligand N-(cyclohexyl... 1 0
5-hydroxytryptamine receptor 2A and Muscarinic acetylcholine r... 1 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 13
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 1


External ID

Functional Category

Molecule Name

CFAMM00394540 CHEMBL1929279 Bioactive 3,3-dimethyl-1-[3-(4,5,6,7-tetrahydro-1-benzothiophen-4-yl)propyl]piperidine;hydrochloride
CFAMM00394539 CHEMBL1929278 Bioactive 1-[3-(1-benzothiophen-4-yl)propyl]-3,3-dimethylpiperidine;hydrochloride
CFAMM00394537 CHEMBL1929280 Bioactive 3,3-dimethyl-1-[5-(4,5,6,7-tetrahydro-1-benzothiophen-4-yl)pentyl]piperidine;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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