CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9356
Family Name Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 receptor EP2 subtype ligand SureCN4936479 family
No. of Seeds 13 No. of Other Members 22
Family Centroid CFAMM00358609 Functional Category Bioactive
Superfamily Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 receptor EP2 subtype ligand SureCN4936479 Superfamily
Class Class 296

Cousin Family NamesSeedsMembers
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 F... 6 8
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Angiotensin-converting enzyme Inhibitor N-carboxymethyl-n-cycl... 2 24
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 2-[4-[[1-(2,... 2 7
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 13
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 4 41
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 2 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-2-[4-(4-fluor... 1 0
Prostaglandin E2 receptor EP4 subtype ligand 7-[(2R)-2-[(E,3S)... 3 4
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 4 14
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 2 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 5 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 5 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 7 9
Malonyl-CoA decarboxylase, mitochondrial inhibitor [4-(1,1,1,3... 6 0
Prostaglandin E2 receptor EP4 subtype ligand 4-[2-[(2R)-2-[(E,... 2 0
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-03OOH7 family 1 2
Dipeptidyl peptidase 4 inhibitor 3-[2-[(4R,5R)-5-amino-2-oxo-4... 1 4
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 1 5
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 3 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 2 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 2 1
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 2 0
Pol polyprotein inhibitor Enantiomer of AG1284 family 7 1
C-C chemokine receptor type 5 ligand AC1LAX0N family 2 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN4203288 family 2 2
Neutrophil elastase inhibitor 4-[(E)-3-[[(2S)-3-methyl-1-oxo-1... 2 6
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 4
Neutrophil elastase inhibitor 3-[[(2S)-3-methyl-1-oxo-1-[2-[(1... 1 0
Huntingtin and Inositol monophosphatase 1 inhibitor CHEMBL1493... 1 1
Prostaglandin D2 receptor 2 ligand 2-[3-[2-[[(4S,5R)-4-methyl-... 2 1
Type-1B angiotensin II receptor ligand AGN-PC-074YOZ family 1 14
2-bromo-N-[(2R)-2-hydroxy-2-phenylethyl]-N-methylbenzamide NP ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394728 CHEMBL272277 Bioactive 4-[2-[(2R)-2-[(E,3S)-3-(1-butylcyclobutyl)-3-hydroxyprop-1-enyl]-5-oxopyrrolidin-1-yl]ethyl]benzoic acid
CFAMM00394742 CHEMBL398947 Bioactive 4-[2-[(2R)-2-[(1E)-4-methylpenta-1,3-dienyl]-5-oxopyrrolidin-1-yl]ethyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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