CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9364
Family Name Neuronal acetylcholine receptor subunit alpha-7 ligand 1-(4-methylsulfanylphenyl)-3-[(2R,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]urea family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00394785 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 48
Class Class 64

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Histamine H1 receptor Ligand Triprolidine Family 19 316
Transient receptor potential cation channel subfamily V member... 15 158
Transient receptor potential cation channel subfamily V member... 16 295
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Amg 423 family 7 47
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 9
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 1 13
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... 16 9
Thyrotropin receptor and Huntingtin ligand CHEMBL1333081 family 1 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Platelet-activating factor receptor ligand YM-461 family 1 11
Nicotinamide phosphoribosyltransferase and Prelamin-A/C inhibi... 1 0
Prostaglandin E synthase inhibitor AGN-PC-09QHBK family 3 1
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 0
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(8-oxa-3... 5 4
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(1-methy... 1 4
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... 4 8
Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-... 2 0
Cytochrome P450 2C9 and Cytochrome P450 1A2 inhibitor SB 22128... 2 0
Platelet-activating factor receptor ligand SureCN9853140 family 3 3
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
Neutrophil elastase and Chymotrypsin-like elastase family memb... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394785 CHEMBL193378 Bioactive 1-(4-methylsulfanylphenyl)-3-[(2R,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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