CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9369
Family Name Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-phenylethyl]carbamoyl]-4-(propanoylamino)phenoxy]phenyl]acetic acid family
No. of Seeds 5 No. of Other Members 28
Family Centroid CFAMM00394814 Functional Category Bioactive with Natural Product
Superfamily Pol polyprotein and Glucagon receptor Binder Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Liga... 17 31
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Adenosine receptor A2a Ligand Methyl 7-methoxy-4-phenylbenzofu... 3 21
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 8 39
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Thyroid hormone receptor beta ligand SureCN8800248 family 3 10
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 18 2
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Integrin alpha-4 inhibitor SureCN14558471 family 16 2
Prostaglandin D2 receptor 2 ligand AGN-PC-07CQC5 family 4 0
Plasminogen activator inhibitor 1 inhibitor 2-[2-methoxy-6-[[4... 1 3
Leukotriene B4 receptor 1 ligand 4-methoxy-3-[[(E)-3-(4-phenyl... 2 10
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Plasminogen activator inhibitor 1 inhibitor 9-hydroxy-3-methox... 1 0
Major prion protein and Microtubule-associated protein tau inh... 2 10
Multidrug resistance protein 1 inhibitor 3,4,5-trimethoxy-N-(2... 4 0
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394814 CHEMBL1933918 Bioactive 2-[4-methoxy-3-[2-[[(1S)-1-phenylethyl]carbamoyl]-4-(propanoylamino)phenoxy]phenyl]acetic acid
CFAMM00394819 CHEMBL1933915 Bioactive 2-[3-[2-[(4-chlorophenyl)methylcarbamoyl]-4-(propanoylamino)phenoxy]-4-methoxyphenyl]acetic acid
CFAMM00394833 CHEMBL1933920 Bioactive 2-[3-[2-[[1-(4-fluorophenyl)-2-methylpropan-2-yl]carbamoyl]-4-(propanoylamino)phenoxy]-4-methoxyphenyl]acetic acid
CFAMM00394815 CHEMBL1933919 Bioactive 2-[3-[2-[2-(4-fluorophenyl)ethylcarbamoyl]-4-(propanoylamino)phenoxy]-4-methoxyphenyl]acetic acid
CFAMM00394821 CHEMBL1933917 Bioactive 2-[3-[2-[[(1S)-1-(4-chlorophenyl)ethyl]carbamoyl]-4-(propanoylamino)phenoxy]-4-methoxyphenyl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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