CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9371
Family Name Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00394856 Functional Category Bioactive
Superfamily Beta-lactamase and Histamine H3 receptor Binder Superfamily 6
Class Class 2035

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Pitolisant family 4 24
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
5-hydroxytryptamine receptor 7 and Sodium-dependent serotonin ... 5 1
Histamine H3 receptor ligand 2-benzyl-4-[4-(2-pyrrolidin-1-yle... 8 4
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 12
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
C-C chemokine receptor type 5 ligand 1-[[(3S,4S)-1-(cyclohexyl... 1 0
Histamine H3 receptor ligand 1-[4-[4-(pyrrolidin-1-ylmethyl)ph... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394855 CHEMBL1934061 Bioactive 1-[[4-[4-[(1S)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
CFAMM00394856 CHEMBL1934060 Bioactive 1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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