CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9373
Family Name Melanin-concentrating hormone receptor 2 ligand N,N-dimethyl-3-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)carbazole-9-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00394863 Functional Category Bioactive
Superfamily Cytochrome P450 2C19 and Melanin-concentrating hormone receptor 2 Binder Superfamily
Class Class 3209

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Transient receptor potential cation channel subfamily V member... 15 158
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Setipiprant family 5 118
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Urotensin-2 receptor Ligand Palosuran Family 4 4
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 3
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Melanin-concentrating hormone receptor 2 ligand (2R)-1'-(9H-ca... 2 10
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Melanin-concentrating hormone receptor 2 and Sodium-dependent ... 2 1
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
Capsid scaffolding protein inhibitor AC1O583J family 5 1
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394863 CHEMBL1934109 Bioactive N,N-dimethyl-3-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)carbazole-9-carboxamide
CFAMM00394862 CHEMBL1934112 Bioactive 3-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)carbazole-9-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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