CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9376
Family Name Melanin-concentrating hormone receptor 2 and Sodium-dependent serotonin transporter ligand N-[(1R)-1'-[(6-chloro-9H-carbazol-3-yl)methyl]spiro[1,2-dihydroindene-3,4'-piperidine]-1-yl]acetamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00191237 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Melanin-concentrating hormone receptor 2 Binder Superfamily 2
Class Class 173

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
Acetylcholinesterase Inhibitor Tacrine Family 12 515
D(2) dopamine receptor Ligand Sertindole Family 3 173
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 43 17
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 10 18
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
Sodium-dependent serotonin transporter inhibitor SureCN6087392... 1 1
D(4) dopamine receptor and D(1A) dopamine receptor ligand 2-[[... 5 4
Prostaglandin G/H synthase 2 inhibitor SureCN6998947 family 1 1
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Melanin-concentrating hormone receptor 2 ligand N,N-dimethyl-3... 2 2
Melanin-concentrating hormone receptor 2 ligand (2R)-1'-(9H-ca... 2 10
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Cathepsin K inhibitor (1R,2R)-2-(6-chloro-1,3,4,5-tetrahydropy... 2 0
5-hydroxytryptamine receptor 6 ligand 9-(2-bromophenyl)sulfony... 2 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 5
Capsid scaffolding protein inhibitor AC1O583J family 5 1
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
Nociceptin receptor and Mu-type opioid receptor ligand SureCN1... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394884 CHEMBL212575 Bioactive SureCN14280677

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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