CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9384
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand (2R)-1-[2-[4-[4-(2-methoxyethylsulfonyl)phenyl]phenyl]ethyl]-2-methylpyrrolidine family
No. of Seeds 14 No. of Other Members 1
Family Centroid CFAMM00394918 Functional Category Bioactive
Superfamily Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 2606

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
5-hydroxytryptamine receptor 1A Ligand 2-(biphenyl-3-ylthio)-n... 1 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394929 CHEMBL1934356 Bioactive (2R)-2-methyl-1-[2-[4-(4-propylsulfonylphenyl)phenyl]ethyl]pyrrolidine
CFAMM00394922 CHEMBL1934524 Bioactive 3-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonylpropan-1-ol
CFAMM00394928 CHEMBL1934357 Bioactive (2R)-2-methyl-1-[2-[4-(4-propan-2-ylsulfonylphenyl)phenyl]ethyl]pyrrolidine
CFAMM00394921 CHEMBL1934523 Bioactive (2R)-1-[2-[4-[4-(3-methoxypropylsulfonyl)phenyl]phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394920 CHEMBL1934522 Bioactive (2R)-1-[2-[4-[4-(2-ethoxyethylsulfonyl)phenyl]phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394926 CHEMBL1934528 Bioactive (2R)-1-[2-[4-[4-(methoxymethylsulfonyl)phenyl]phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394919 CHEMBL1934521 Bioactive 2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonylethanol
CFAMM00394925 CHEMBL1934527 Bioactive (2R)-2-methyl-1-[2-[4-[4-(oxan-2-ylmethylsulfonyl)phenyl]phenyl]ethyl]pyrrolidine
CFAMM00394918 CHEMBL1934520 Bioactive (2R)-1-[2-[4-[4-(2-methoxyethylsulfonyl)phenyl]phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394931 CHEMBL1934358 Bioactive (2R)-1-[2-[4-(4-benzylsulfonylphenyl)phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394924 CHEMBL1934526 Bioactive (2R)-2-methyl-1-[2-[4-[4-(oxan-4-ylsulfonyl)phenyl]phenyl]ethyl]pyrrolidine
CFAMM00394917 CHEMBL1934519 Bioactive (2R)-1-[2-[4-(4-cyclopentylsulfonylphenyl)phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394930 CHEMBL1934355 Bioactive (2R)-1-[2-[4-(4-ethylsulfonylphenyl)phenyl]ethyl]-2-methylpyrrolidine
CFAMM00394923 CHEMBL1934525 Bioactive (2R)-2-methyl-1-[2-[4-[4-(oxan-4-ylmethylsulfonyl)phenyl]phenyl]ethyl]pyrrolidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

69507 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543