CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9392
Family Name Melanin-concentrating hormone receptor 1 ligand N-[3-[1-[3-[4-(2,4-difluorophenyl)-1-oxophthalazin-2-yl]propyl]piperidin-4-yl]phenyl]acetamide family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00394995 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Ferritin light chain Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor KU-0059436 Family 21 45
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Poly [ADP-ribose] polymerase 1 Inhibitor KU-58684 Family 6 40
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 8
Adenosine receptor A3 ligand AGN-PC-09M0WF family 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
B1 bradykinin receptor ligand 4-(4-methyl-1-oxophthalazin-2-yl... 5 27
Poly [ADP-ribose] polymerase 1 inhibitor 8-[[4-fluoro-3-(4-phe... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 5
Aldose reductase inhibitor 2-[3-[2-(3-fluoroanilino)-2-oxoethy... 3 4
Inosine-5'-monophosphate dehydrogenase inhibitor N-(3,4-dichlo... 2 1
Inosine-5'-monophosphate dehydrogenase inhibitor N-[4-bromo-3-... 1 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor 4-N-m... 3 11


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00394996 CHEMBL1934835 Bioactive N-[3-[1-[3-[4-(3,4-difluorophenyl)-1-oxophthalazin-2-yl]propyl]piperidin-4-yl]phenyl]acetamide
CFAMM00394989 CHEMBL1934826 Bioactive N-[3-[1-[3-[4-(4-fluorophenyl)-1-oxophthalazin-2-yl]propyl]piperidin-4-yl]phenyl]acetamide
CFAMM00394995 CHEMBL1934834 Bioactive N-[3-[1-[3-[4-(2,4-difluorophenyl)-1-oxophthalazin-2-yl]propyl]piperidin-4-yl]phenyl]acetamide
CFAMM00394997 CHEMBL1934839 Bioactive N-[3-[1-[3-[4-(4-chloro-3-fluorophenyl)-1-oxophthalazin-2-yl]propyl]piperidin-4-yl]phenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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