CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9397
Family Name Macrophage metalloelastase inhibitor (2S)-3-methyl-2-[[8-(5-methylthiophen-2-yl)dibenzofuran-3-yl]sulfonylamino]butanoic acid family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00395043 Functional Category Bioactive
Superfamily Prostacyclin receptor and Prostaglandin D2 receptor Binder Superfamily
Class Class 2267

Cousin Family NamesSeedsMembers
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 45
Collagenase 3 and 72 kDa type IV collagenase inhibitor SureCN1... 8 50
Collagenase 3 and A disintegrin and metalloproteinase with thr... 10 19
Macrophage metalloelastase inhibitor (2S)-3-methyl-2-[[8-(5-me... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 2 0
Prothrombin inhibitor 1-[5-(diaminomethylideneamino)-2-(dibenz... 1 4
Prostaglandin D2 receptor and Prostacyclin receptor ligand Sur... 3 6
Beta-lactamase inhibitor CHEMBL1410579 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00395043 CHEMBL1935288 Bioactive (2S)-3-methyl-2-[[8-(5-methylthiophen-2-yl)dibenzofuran-3-yl]sulfonylamino]butanoic acid
CFAMM00395040 CHEMBL1935284 Bioactive (2S)-2-[[8-(furan-3-yl)dibenzofuran-3-yl]sulfonylamino]-3-methylbutanoic acid
CFAMM00395039 CHEMBL1935287 Bioactive (2S)-3-methyl-2-[(8-thiophen-2-yldibenzofuran-3-yl)sulfonylamino]butanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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