CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9405
Family Name Histamine H4 receptor and Histamine H3 receptor ligand 7-(furan-3-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00288924 Functional Category Bioactive
Superfamily Prelamin-A/C and Histamine H4 receptor Binder Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-... 2 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 0
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 1 0
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Dihydrofolate reductase inhibitor 3-(2,4-diamino-6-methylquina... 2 1
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
5-hydroxytryptamine receptor 3A and Histamine H4 receptor liga... 1 0
Dual specificity protein kinase CLK4 and Dual specificity tyro... 6 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 2
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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