CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9418
Family Name Renin and Cytochrome P450 3A4 inhibitor SureCN6719989 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00279006 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Renin Binder Superfamily
Class Class 3218

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Substance-K receptor Ligand MEN-14933 Family 13 154
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Renin Inhibitor Ro-66-1168 Family 10 30
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Renin inhibitor 6-[[(2R)-1-[4-[3-[(2-methoxyphenyl)methoxy]pro... 3 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 8 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Substance-P receptor ligand (2S,4S)-1-N-(3-chlorophenyl)-2-N-[... 5 2
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Furin inhibitor phenyl 2-[[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbami... 2 5
C-C chemokine receptor type 1 ligand N-[2-[(2S)-2-amino-3-(5-f... 3 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 3
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Histone deacetylase 8 and Histone deacetylase 6 inhibitor (3S)... 4 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395227 CHEMBL382030 Bioactive 6-[[(2R)-1-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-6-oxopiperazin-2-yl]methoxy]-4-(3-methoxypropyl)-1,4-benzoxazin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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