CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM942
Family Name Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 receptor EP4 subtype ligand SureCN2982707 family
No. of Seeds 8 No. of Other Members 12
Family Centroid CFAMM00185224 Functional Category Bioactive
Superfamily Microsomal triglyceride transfer protein large subunit Inhibitor SLX-4090 Superfamily
Class Class 1003

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Peroxisome proliferator-activated receptor alpha Ligand Bezafi... 2 17
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 4 7
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
B1 bradykinin receptor ligand 4-(5-chloro-4-oxochromen-3-yl)-N... 1 5
Growth hormone secretagogue receptor type 1 ligand 2-[(2S)-1-[... 2 0
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 14 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 15 13
Caspase-1 inhibitor (3S)-3-[2-[3-(naphthalene-1-carbonylamino)... 13 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6627432 f... 6 1
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 0
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2-chlo... 2 4
Metabotropic glutamate receptor 2 ligand SureCN787402 family 1 8
M1 family aminopeptidase and Aminopeptidase N inhibitor N-[(4-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317665 CHEMBL605991 Bioactive AGN-PC-03XH7O
CFAMM00317664 CHEMBL597786 Bioactive AGN-PC-03XGVV
CFAMM00317657 CHEMBL597348 Bioactive AGN-PC-03XGPF
CFAMM00317663 CHEMBL597552 Bioactive AGN-PC-03XGG8
CFAMM00317670 CHEMBL600219 Bioactive SureCN2970681
CFAMM00317675 CHEMBL599810 Bioactive AGN-PC-03XGZW

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26197 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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