CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9421
Family Name C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00395251 Functional Category Bioactive
Superfamily C-X-C chemokine receptor type 3 Binder Superfamily
Class Class 4714

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand TAK-637 Family 18 63
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-chlorop... 4 0
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... 4 0
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[4-oxo-3-(4-p... 2 1
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-cyanoph... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395254 CHEMBL578197 Bioactive SureCN12659801
CFAMM00395247 CHEMBL1939692 Bioactive N-[(1,1-dioxothian-4-yl)methyl]-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide
CFAMM00395253 CHEMBL571080 Bioactive SureCN13151077
CFAMM00395251 CHEMBL1939554 Bioactive N-[(1R)-1-[3-(4-cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[3-fluoro-4-(trifluoromethyl)phenyl]acetamide
CFAMM00395250 CHEMBL1939562 Bioactive N-[(1,1-dioxothian-4-yl)methyl]-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide
CFAMM00395256 CHEMBL1938408 Bioactive N-[(1R)-1-[3-(4-cyanophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1,1-dioxothian-4-yl)methyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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