CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9432
Family Name Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 inhibitor 4-amino-2-(4-tert-butylphenyl)-N-methylthieno[3,2-c]pyridine-7-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00329673 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Cyclin-dependent kinase 7 Binder Superfamily
Class Class 3155

Cousin Family NamesSeedsMembers
Aurora kinase A Inhibitor ABT-348 Family 20 49
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-(4... 3 9
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
Gonadotropin-releasing hormone receptor ligand 1-[4-[1-[(2,6-d... 8 0
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 1 0
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
Histone deacetylase 1 and Potassium voltage-gated channel subf... 3 2
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
Ephrin type-B receptor 4 ligand SureCN4473188 family 3 1
Mitogen-activated protein kinase kinase kinase 8 inhibitor AGN... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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