CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9464
Family Name B1 bradykinin receptor ligand N-[(1R)-6-[(dimethylamino)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]acetamide family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00395703 Functional Category Bioactive
Superfamily B1 bradykinin receptor and B2 bradykinin receptor Binder Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Neutrophil elastase inhibitor 2-[3-(benzylsulfamoylamino)-2-ox... 5 27
B1 bradykinin receptor ligand SureCN4136698 family 6 33
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
B1 bradykinin receptor ligand 2-[1-(4-chlorophenyl)sulfonyl-3-... 5 9
B1 bradykinin receptor ligand SureCN13936521 family 19 4
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
B1 bradykinin receptor ligand N-[(4R)-1,1-dioxo-3,4-dihydro-2H... 1 0
B1 bradykinin receptor ligand N-[(4S)-1-ethyl-3,3-dimethylpipe... 10 4
Proteasome subunit beta type-5 inhibitor (2S)-N'-(2,2-dimethyl... 2 9
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 1 0
B1 bradykinin receptor ligand SureCN5950627 family 2 11
Motilin receptor ligand N-[[2-[4-[[(3S,5R)-3,5-dimethylpiperaz... 2 0
B1 bradykinin receptor ligand SureCN5405184 family 1 0
B1 bradykinin receptor ligand SureCN5392679 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395705 CHEMBL1939759 Bioactive N-[(1R)-6-[(cyclopropylamino)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]acetamide
CFAMM00395704 CHEMBL1939758 Bioactive 2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]-N-[(1R)-6-(pyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide
CFAMM00395703 CHEMBL1939757 Bioactive N-[(1R)-6-[(dimethylamino)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]acetamide
CFAMM00395702 CHEMBL1939756 Bioactive N-[(1R)-6-(aminomethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]acetamide
CFAMM00395701 CHEMBL1939755 Bioactive 2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide
CFAMM00395700 CHEMBL1939760 Bioactive N-[(1R)-6-[(2,2-dimethylpropylamino)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]acetamide
CFAMM00395699 CHEMBL1939761 Bioactive 2-[(3R)-4-(4-methylphenyl)sulfonyl-2-oxo-1,3-dihydropyrazin-3-yl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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