CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9474
Family Name Collagenase 3 and Matrix metalloproteinase-14 inhibitor 4-[[[5-(2-ethoxycarbonyl-1H-indol-5-yl)-1-methylpyrazole-3-carbonyl]amino]methyl]benzoic acid family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00395766 Functional Category Bioactive
Superfamily Cathepsin S and Collagenase 3 Binder Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Huntingtin and Alkaline phosphatase, tissue-nonspecific isozym... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395766 CHEMBL1939876 Bioactive 4-[[[5-(2-ethoxycarbonyl-1H-indol-5-yl)-1-methylpyrazole-3-carbonyl]amino]methyl]benzoic acid
CFAMM00395765 CHEMBL1939877 Bioactive 2-[4-[[[5-(2-ethoxycarbonyl-1H-indol-5-yl)-1-methylpyrazole-3-carbonyl]amino]methyl]phenyl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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