CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9475
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL23992 family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00395779 Functional Category Bioactive with Natural Product
Superfamily cGMP-specific 3',5'-cyclic phosphodiesterase and Adenosine receptor A2b Binder Superfamily
Class Class 253

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Prelamin-A/C inhibitor CHEMBL1501476 family 1 2
Survival motor neuron protein and Microtubule-associated prote... 2 14
C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S... 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 10 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
Sodium- and chloride-dependent glycine transporter 1 and Potas... 14 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395780 CHEMBL362938 Bioactive (7R)-7-benzyl-5-ethyl-1-[(4-hydroxyphenyl)methyl]-2-(2-phenylethynyl)-7,8-dihydroimidazo[2,1-b]purin-4-one
CFAMM00395773 CHEMBL370413 Bioactive (7R)-7-benzyl-2-bromo-5-ethyl-1-[(4-hydroxyphenyl)methyl]-7,8-dihydroimidazo[2,1-b]purin-4-one
CFAMM00395779 CHEMBL23992 Bioactive CHEMBL23992
CFAMM00395772 CHEMBL26396 Bioactive CHEMBL26396
CFAMM00395778 CHEMBL487704 Bioactive CHEMBL487704
CFAMM00395771 CHEMBL280525 Bioactive CHEMBL280525
CFAMM00395777 CHEMBL193989 Bioactive SureCN8362680
CFAMM00395770 CHEMBL282189 Bioactive CHEMBL282189
CFAMM00395783 CHEMBL365944 Bioactive (7R)-7-benzyl-5-ethyl-3-[(4-hydroxyphenyl)methyl]-2-(2-phenylethynyl)-7,8-dihydroimidazo[2,1-b]purin-4-one
CFAMM00395782 CHEMBL365358 Bioactive (7R)-7-benzyl-5-ethyl-3-[(4-hydroxyphenyl)methyl]-2-iodo-7,8-dihydroimidazo[2,1-b]purin-4-one
CFAMM00395775 CHEMBL282709 Bioactive CHEMBL282709
CFAMM00395781 CHEMBL280624 Bioactive CHEMBL280624

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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