CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9490
Family Name D(4) dopamine receptor and D(2) dopamine receptor ligand 4-(4-chlorophenyl)-1-[3-(4-fluorophenoxy)propyl]piperidin-4-ol family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00395917 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and Histamine H3 receptor Binder Superfamily
Class Class 3413

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Histamine H1 receptor Ligand Clemastine Family 5 76
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Glutamate receptor ionotropic, NMDA 3A and Glutamate receptor ... 2 1
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 21
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Histamine H1 receptor and C-C chemokine receptor type 3 ligand... 2 2
Histamine H3 receptor ligand AGN-PC-0765YW family 1 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 14 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 4 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
C-C chemokine receptor type 1 ligand SureCN9111242 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395919 CHEMBL1946122 Bioactive (1S,5R)-3-(4-chlorophenyl)-8-[3-(4-fluorophenoxy)propyl]-8-azabicyclo[3.2.1]octan-3-ol
CFAMM00395917 CHEMBL1940404 Bioactive 4-(4-chlorophenyl)-1-[3-(4-fluorophenoxy)propyl]piperidin-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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