CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9492
Family Name D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A ligand 1-(4-chlorophenyl)-4-[3-(4-fluorophenoxy)propyl]piperazine family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00279901 Functional Category Bioactive
Superfamily D(2) dopamine receptor Ligand Loxapine Superfamily
Class Class 217

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-[... 2 1
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 1 0
Alpha-1D adrenergic receptor and D(2) dopamine receptor ligand... 3 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-0034EG family 5 2
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Prelamin-A/C and Nonstructural protein 1 inhibitor CHEMBL14536... 1 2
D(2) dopamine receptor and D(3) dopamine receptor ligand 1-(3-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27278 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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