CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9496
Family Name Vasopressin V1a receptor ligand (2R)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-(4-piperidin-1-ylpiperidin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide family
No. of Seeds 35 No. of Other Members 24
Family Centroid CFAMM00396006 Functional Category Bioactive
Superfamily Vasopressin V1a receptor Binder Superfamily
Class Class 4720

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor ligand benzyl 4,4-dimethyl-3-oxo-2-[(... 2 5
Vasopressin V1a receptor ligand (2S)-5-(4-cyclohexylpiperazin-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00395980 CHEMBL439398 Bioactive 3-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-3-(4-piperidin-1-ylpiperidin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]propanamide
CFAMM00395993 CHEMBL1940587 Bioactive (2R)-2-[(2R,3S)-2-[(E)-2-(3-fluorophenyl)ethenyl]-4-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]azetidin-1-yl]-4-oxo-N-[(1R)-1-phenylethyl]-4-(4-piperidin-1-ylpiperidin-1-yl)butanamide
CFAMM00396006 CHEMBL389359 Bioactive (2R)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-(4-piperidin-1-ylpiperidin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395986 CHEMBL396954 Bioactive (2S)-5-[4-(cyclohexylmethyl)piperazin-1-yl]-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395973 CHEMBL388259 Bioactive (2S)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-[4-(2-piperidin-1-ylethyl)piperidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395999 CHEMBL439462 Bioactive (2S)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-5-[4-(piperidin-1-ylmethyl)piperidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395966 CHEMBL394829 Bioactive (2S)-4-(4-amino-1-benzylpiperidin-1-ium-1-yl)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395959 CHEMBL438319 Bioactive (2S)-5-(4-cyclohexylpiperazin-1-yl)-N-[(3,5-difluorophenyl)methyl]-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]pentanamide
CFAMM00395985 CHEMBL396955 Bioactive (2S)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-5-(4-propylpiperazin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395998 CHEMBL427810 Bioactive (2S)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-5-[4-(2-phenylethyl)piperazin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395965 CHEMBL389360 Bioactive (2R)-4-(4-amino-1-benzylpiperidin-1-ium-1-yl)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395978 CHEMBL394866 Bioactive (2S)-5-(4-cyclohexylpiperazin-1-yl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]pentanamide
CFAMM00396004 CHEMBL394830 Bioactive (2S)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-(4-piperidin-1-ylpiperidin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395971 CHEMBL411757 Bioactive (2S)-5-(4-cyclohexylpiperazin-1-yl)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395984 CHEMBL241826 Bioactive 3-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-3-[4-(2-piperidin-1-ylethyl)piperidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]propanamide
CFAMM00396010 CHEMBL397185 Bioactive (2S)-5-(4-cyclohexylpiperazin-1-yl)-N-[[2-fluoro-5-(trifluoromethyl)phenyl]methyl]-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]pentanamide
CFAMM00395977 CHEMBL394867 Bioactive (2S)-5-(4-cyclohexylpiperazin-1-yl)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395990 CHEMBL409370 Bioactive (2R)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-[4-(piperidin-1-ylmethyl)piperidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395996 CHEMBL427816 Bioactive (2S)-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N'-(2-piperidin-1-ylethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]pentanediamide
CFAMM00395963 CHEMBL245072 Bioactive (2S)-4-(4-benzyl-1,4-diazepan-1-yl)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395976 CHEMBL245115 Bioactive (2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-cyclohexylpiperazin-1-yl)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]pentanamide
CFAMM00396002 CHEMBL397025 Bioactive (2S)-N-[[2-fluoro-3-(trifluoromethyl)phenyl]methyl]-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-(4-piperidin-1-ylpiperidin-1-yl)butanamide
CFAMM00395956 CHEMBL279328 Bioactive (2R)-N-methyl-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-(4-piperidin-1-ylpiperidin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395969 CHEMBL411629 Bioactive (2S)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-5-(4-piperidin-1-ylpiperidin-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395982 CHEMBL395817 Bioactive (2R)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[(1R)-1-phenylethyl]-4-(4-piperidin-1-ylpiperidin-1-yl)butanamide
CFAMM00395995 CHEMBL1940588 Bioactive (2R)-2-[(2R,3S)-2-[(E)-2-(3-methylphenyl)ethenyl]-4-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]azetidin-1-yl]-4-oxo-N-[(1R)-1-phenylethyl]-4-(4-piperidin-1-ylpiperidin-1-yl)butanamide
CFAMM00395962 CHEMBL244243 Bioactive (2R)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-(4-piperidin-1-ylpiperidin-1-yl)-N-[(1R)-1-[3-(trifluoromethyl)phenyl]ethyl]butanamide
CFAMM00395975 CHEMBL241305 Bioactive (2R)-5-(4-cyclohexylpiperazin-1-yl)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395988 CHEMBL411960 Bioactive (2S)-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-5-[4-(2-piperidin-1-ylethyl)piperidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]pentanamide
CFAMM00395968 CHEMBL395778 Bioactive 3-(4-butylpiperazin-1-yl)-3-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]propanamide
CFAMM00395981 CHEMBL397179 Bioactive (2S)-5-(4-cyclohexylpiperazin-1-yl)-N-[[2-fluoro-3-(trifluoromethyl)phenyl]methyl]-5-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]pentanamide
CFAMM00395994 CHEMBL1940586 Bioactive (2R)-2-[(2R,3S)-2-[(E)-2-(3-iodophenyl)ethenyl]-4-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]azetidin-1-yl]-4-oxo-N-[(1R)-1-phenylethyl]-4-(4-piperidin-1-ylpiperidin-1-yl)butanamide
CFAMM00395961 CHEMBL409561 Bioactive (2R)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-4-[4-(2-piperidin-1-ylethyl)piperidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00395974 CHEMBL388258 Bioactive (2S)-4-[(3S)-3-amino-1-benzylpyrrolidin-1-ium-1-yl]-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide
CFAMM00396000 CHEMBL397026 Bioactive (2S)-4-oxo-2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-N-[(1S)-1-phenylethyl]-4-[4-(2-piperidin-1-ylethyl)piperidin-1-yl]butanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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