CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9508
Family Name Glycogen synthase kinase-3 beta inhibitor CHEMBL1940990 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00396104 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta Binder Superfamily 5
Class Class 110

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Glycogen synthase kinase-3 beta inhibitor CHEMBL1940907 family 2 21
Glycogen synthase kinase-3 beta inhibitor CHEMBL1940986 family 1 0
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 3 3
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 1 2
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 6 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 1 0
B2 bradykinin receptor ligand 1-N,3-N-dimethyl-4-[methyl-[2-[[... 4 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396103 CHEMBL1940976 Bioactive CHEMBL1940976
CFAMM00396099 CHEMBL1940989 Bioactive CHEMBL1940989
CFAMM00396104 CHEMBL1940990 Bioactive CHEMBL1940990

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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