CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9512
Family Name Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxytryptamine receptor 3E ligand SureCN4194893 family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00396112 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Prothrombin Binder Superfamily
Class Class 2613

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 4 3
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family 6 6
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-09M88E f... 1 7
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 0
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Histamine H3 receptor ligand AGN-PC-00CW2Z family 1 2
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 3 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 5 14
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(p... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
Histone deacetylase 1 inhibitor AGN-PC-007IQK family 1 4
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 8 6
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN1564756 f... 1 0
Carbonic anhydrase 2 inhibitor AGN-PC-07C00S family 4 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0
Peptide deformylase inhibitor N-[(2S)-1-[cyclopentylmethyl-[2-... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 1
Lethal(3)malignant brain tumor-like protein 1 and Nuclear rece... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 0
Histone deacetylase 6 inhibitor AGN-PC-0C7PT7 family 4 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396115 CHEMBL370535 Bioactive acetic acid;N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-5-phenylthiophene-2-carboxamide
CFAMM00396114 CHEMBL195190 Bioactive AGN-PC-075WOG
CFAMM00396113 CHEMBL208565 Bioactive SureCN5917914
CFAMM00396112 CHEMBL194100 Bioactive SureCN4194893
CFAMM00396119 CHEMBL195329 Bioactive SureCN372893

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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