CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM952
Family Name Metabotropic glutamate receptor 5 ligand [18F]FDEGPECO family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00317832 Functional Category Bioactive
Superfamily Peptide deformylase, mitochondrial Inhibitor Hydroxy[3-(6-methylpyridin-2-yl)propyl]formamide Superfamily
Class Class 1905

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-(4-phenylb... 6 32
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Farnesyl pyrophosphate synthase Inhibitor Piridronic Acid Family 3 14
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Fatty-acid amide hydrolase 1 Inhibitor 6-fluoropyridin-3-ylbor... 1 2
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Metabotropic glutamate receptor 5 ligand AGN-PC-075X3R family 1 1
Nuclear receptor ROR-gamma and Prelamin-A/C ligand 13463-41-7 ... 1 7
N-[2-(1-oxidopyridin-1-ium-2-yl)ethyl]-N-phenylacetamide NP 2-... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00317832 CHEMBL1094474 Bioactive [18F]FDEGPECO
CFAMM00317838 CHEMBL2164785 Bioactive (Z)-N-ethoxy-6-fluoro-3-(2-pyridin-2-ylethynyl)cyclohex-2-en-1-imine
CFAMM00317836 CHEMBL1094805 Bioactive (E)-N-(2-fluoroethoxymethoxy)-3-(2-pyridin-2-ylethynyl)cyclohex-2-en-1-imine
CFAMM00317835 CHEMBL1094807 Bioactive (E)-N-[2-(2-fluoroethoxy)ethoxy]-3-(2-pyridin-2-ylethynyl)cyclohex-2-en-1-imine
CFAMM00317834 CHEMBL1094806 Bioactive (E)-N-(3-fluoropropoxymethoxy)-3-(2-pyridin-2-ylethynyl)cyclohex-2-en-1-imine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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