CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9520
Family Name Metabotropic glutamate receptor 5 ligand AGN-PC-075X3Y family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00372846 Functional Category Bioactive
Superfamily Substance-P receptor and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 900

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Atazanavir Family 16 58
5-hydroxytryptamine receptor Ligand Metergolin Family 2 11
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 12
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 1 7
Neutrophil elastase inhibitor SureCN7284457 family 4 6
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5351665 fa... 5 4
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16b ... 2 0
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7013744... 2 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 4
Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6... 1 0
Putative NP ZINC03999154 Family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396146 CHEMBL219060 Bioactive SureCN5348026

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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