CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9525
Family Name Prothrombin inhibitor SureCN6925359 family
No. of Seeds 6 No. of Other Members 18
Family Centroid CFAMM00396179 Functional Category Bioactive
Superfamily Cruzipain and Prothrombin Binder Superfamily 2
Class Class 974

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Histamine H4 receptor and Histamine H3 receptor ligand SureCN6... 17 51
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
5-hydroxytryptamine receptor 1F ligand AGN-PC-075AYH family 2 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Vascular endothelial growth factor receptor 1 and Vascular end... 11 38
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Histamine H4 receptor ligand 8-chloro-4-[(3R)-3-(methylamino)p... 1 1
Prothrombin and Coagulation factor X inhibitor SureCN6929748 f... 6 5
Prothrombin and Trypsin-1 inhibitor SureCN6930543 family 10 0
Prothrombin inhibitor SureCN6931925 family 3 0
Prothrombin inhibitor SureCN6932678 family 1 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 5 0
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1
Diacylglycerol O-acyltransferase 1 inhibitor ethyl 4-[5-[[2-(3... 5 8
Diacylglycerol O-acyltransferase 1 and Cytochrome P450 3A4 inh... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396171 CHEMBL439678 Bioactive SureCN6929702
CFAMM00396183 CHEMBL194316 Bioactive AGN-PC-00F8TP
CFAMM00396176 CHEMBL198436 Bioactive SureCN6927686
CFAMM00396180 CHEMBL198923 Bioactive SureCN6929620
CFAMM00396179 CHEMBL194560 Bioactive SureCN6925359

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27293 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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