CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9529
Family Name Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 15 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00296448 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 4 4
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 3 13
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 4
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0A9RFQ f... 2 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
G-protein coupled bile acid receptor 1 ligand 2-ethyl-6-[3-[4-... 4 6
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 2 2
Nuclear receptor ROR-gamma and Prelamin-A/C ligand ST50133141 ... 1 0
Tyrosine-protein kinase Lck inhibitor SureCN374434 family 1 1
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL4... 2 3


External ID

Functional Category

Molecule Name

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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