CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9531
Family Name Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]-4-nitroaniline family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00396212 Functional Category Bioactive
Superfamily Histamine H3 receptor Binder Superfamily 5
Class Class 1685

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Beta-secretase 1 inhibitor SureCN3599637 family 1 0
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Histamine H3 receptor ligand SureCN2785624 family 2 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
Histamine H3 receptor ligand 3-[[2-[2-[(2R)-2-methylpyrrolidin... 3 1
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Neuropeptide Y receptor type 1 ligand 1-(1-benzofuran-6-yl)-3-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396213 CHEMBL380557 Bioactive 2,2,2-trifluoro-1-[4-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methylamino]phenyl]ethanone
CFAMM00396212 CHEMBL198325 Bioactive N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]-4-nitroaniline
CFAMM00396210 CHEMBL194620 Bioactive N-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methyl]-2-nitroaniline
CFAMM00396208 CHEMBL194418 Bioactive 3-[[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]methylamino]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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