CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM9535
Family Name Nitric oxide synthase, inducible and Nitric oxide synthase, brain inhibitor 4-[(3-chloro-N-pyrazin-2-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00396232 Functional Category Bioactive
Superfamily GABA theta subunit and Nitric oxide synthase, brain Binder Superfamily
Class Class 930

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Reverse transcriptase Inhibitor PT-109 Family 6 7
Prothrombin inhibitor SureCN5854779 family 4 9
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 21
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762YG family 2 2
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 3 2
Macrophage colony-stimulating factor 1 receptor ligand N-[3-[(... 5 0
Transient receptor potential cation channel subfamily V member... 3 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 3 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00396232 CHEMBL1944717 Bioactive 4-[(3-chloro-N-pyrazin-2-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46119 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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